Search results for "heart protection"

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Association between toenail scandium levels and risk of acute myocardial infarction in European men: the EURAMIC and Heavy Metals Study

2002

The association between scandium status and risk of acute myocardial infarction (MI) was examined in a multicentre case control study in 10 centres from Europe and Israel. Scandium in toenails was assessed in 684 cases and 724 controls less than 70 years of age. Mean concentrations of toenail scandium were 6.74 micro/kg in cases and 7.75 microg/kg in controls. Scandium among controls, adjusted for age and centre was positively associated with concentrations of lycopene and oleic acid in adipose tissue (P = 0.002 for both nutrients). Pearson correlations adjusted for age and centre were significant (P0.05) between scandium and lycopene (r = 0.08), zinc (r = 0.08), mercury (r = 0.18) and olei…

Male0301 basic medicinetissue levelcorrelation analysisHealth Toxicology and MutagenesisscandiumMyocardial Infarction010501 environmental sciencesalpha tocopherolToxicology01 natural sciencesGastroenterologychemistry.chemical_compoundLycopeneRisk Factorsmetal recoveryScandiumMyocardial infarctionFamily historyseleniumRare earth elementsbeta carotenefamily historyadultarticlerisk assessmentMiddle AgedLycopeneadipose tissueHeavy metalsHealthdiabetes mellitusBiological MarkersAntioxidantRisk assessmentcardiovascular riskmedicine.medical_specialtymercuryhypertensiontoealcohol consumptionchemistry.chemical_elementPhysiological Sciencessmokingheart protectioncoronary risk03 medical and health sciencesInternal medicineDiabetes mellitusmedicineHumanscontrolled studyhuman0105 earth and related environmental sciences030102 biochemistry & molecular biologybusiness.industryPublic Health Environmental and Occupational HealthCase-control studyheavy metalcase control studymedicine.diseasemajor clinical studybody massbody burdenSurgeryacute heart infarctionoleic acidNailschemistryCase-Control Studiesalpha-TocopherolbusinessScandiumBiomarkersToxicology and Industrial Health
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Statins, Fracture Risk, and Bone Remodeling: What Is True?

2006

Besides the action on plasma lipid levels, statins show a series of ancillary effects defined as all of their vascular and nonvascular effects independent from the cholesterol reduction. It has been recently hypothesized that one of these ancillary effects could be the improvement of bone health, due to the interference with bone metabolism. This may potentially represent the rationale for statins' use in the treatment of osteoporosis, the most common disease of the bone. Both experimental observations and clinical studies on this topic generated a number of conflicting results; however, the largest randomized clinical trials, the Scandinavian Simvastatin Survival Study (4S), Long Term Inte…

MaleRiskSimvastatinmedicine.medical_specialtyOsteoporosisMyocardial IschemiaBioinformaticsBone remodelinglaw.inventionFractures Bonechemistry.chemical_compoundRandomized controlled trialRisk FactorslawHumansMedicineLongitudinal StudiesRisk factorPravastatinRandomized Controlled Trials as Topicbusiness.industryCholesterolOsteoporosiStatinnutritional and metabolic diseasesGeneral Medicinemedicine.diseaseSurgerychemistrySimvastatinOsteoporosisFemalelipids (amino acids peptides and proteins)Bone RemodelingTherapyHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessFracturesHeart Protection StudyPravastatinmedicine.drugThe American Journal of the Medical Sciences
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